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At low concentrations (0.01 nM), MMP1 and MMP2 gene expression increases, facilitating removal of damaged ECM proteins

Unsaturated PUFAs, especially arachidonic acid (AA) and adrenoyl acid (AdA), are prone to react with ROS, leading to lipid peroxidation and inducing cell ferroptosis

The genes are annotated based on their involvement in metabolism, lipid processing, antiviral responses (HBV/HCV), and susceptibility to liver diseases including cirrhosis and cancer