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C.Navarro-MarJ

DUB USP17 eliminates the K48 ubiquitin chain on NRF2, resulting in camptothecin and paclitaxel resistance in colorectal cancer [270]

(2010) demonstrated through knockout experiments that Nrf2-deficient mice exhibited heightened susceptibility to the MPTP-induced PD model, resulting in significantly lower survival rates of dopaminergic neurons