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In symptomatic Wilson disease the therapeutic goal is to stop progression of liver disease, reversal or improvement of extrahepatic manifestation, and allow an almost normal life expectancy, which in most cases is achievable by the conventional medical therapy (88)

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doi:10.1016/j.cellsig.2013.06.007

BT474 cells and PC3- hTERT cells were cultured in DMEM F-12 medium (Gibco, Invitrogen) with 10% FBS (Gibco, Invitrogen) and 1% PenicillinStreptomycin (Gibco)

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