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J Neuroimmunol (2014) 273(1-2):17

The inclusion of participants experiencing these hormonal changes may be another limitation of the study

For practical purposes, the conversion of DCA to glyoxylate determines the pharmacokinetics of elimination of DCA, thus knowledge of the factors that influence the rate and extent of GSTZ1-1-catalyzed DCA metabolism in people is important for safe and effective dosing of patients