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140,141 Microfilament, also known as actin filament, is one of the main elements of the cytoskeleton, supporting the shape of the cell and maintaining the cellular architecture

It acts directly by neutralizing free radicals, thus protecting cells from oxidative damage, which is essential for preventing chronic diseases and maintaining cellular health over time

For the MTT assay, Calu-3, Huh7.5, and A549 cells were treated with phenformin in concentrations of 6400 M to 0.2 M and atpenin A5 in concentrations of 640 M to 0.15 M in two-fold dilution for 72 h