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23 Further high-quality studies are needed to confirm the results of this RCT with appropriate enrollment and follow-up of a validated outcome in a generalizable setting

Fibroblasts and endothelial cells also significantly influence pigmentation, with fibroblasts affecting melanocyte proliferation and pigmentation through MAPK and WNT/-catenin pathways, while endothelial cells stimulate and inhibit pigmentation

(C) Activated microglia could also stimulate the endothelial expression of intracellular adhesion molecule 1 (ICAM1) from peripheral inflammatory pain stimulation, to alter the permeability of blood-brain barrier

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In vivo magnetic resonance spectroscopy in chronic fatigue syndrome