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Consistent with these studies, a recent study in healthy NS workers demonstrated that moderate alcohol consumption further altered peripheral clock gene amplitude in CLOCK, BMAL1, PER1, CRY1, and CRY2, and it was associated with increased colonic permeability, highlighting the compounding effects of environmental circadian disruption and lifestyle factors on peripheral clock gene regulation 143

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AGEs vernetzen Kollagen quer, was es steif und brchig macht, was einer der Hauptmechanismen der Hautalterung ist