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Zhang L, Chen L, Li C, Shi H, Wang Q, Yang W, Fang L, Leng Y, Sun W, Li M, et al

Preclinical studies in rodent models of cortical contusion and ischemia/reperfusion injury consistently demonstrate that riboflavin administration (typically 120 mg/kg oral or parenteral) reduces lesion volume, brain edema, astrocytosis, and apoptotic cell death, while enhancing sensorimotor recovery and spatial memory performance (8)