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Risk of Bias Assessment The risk of bias was assessed using the SYRCLE's risk of bias tool ( Quantitative Data Synthesis Means and standard deviations (SDs) of the infarct size measurements in the included studies were pooled as weighted mean difference (WMD) with 95% confidence interval (CI) using the DerSimonian and Laird random-effects model to address inter-study heterogeneity

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Thus, the neuroinflammation-induced chain reactions accelerate the imbalance, leading to profound excitotoxicity

( E ) Pearsons correlation coefficients between EGFP-TMEM192 and mScarlet-ER in cells with or without STARD3 expression and with or without CHIR99021 treatment