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10.3390/ijms24043748 40 MoreiraJ.MachadoM.Dias-TeixeiraM.FerrazR.Delerue-MatosC.GrossoC

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Fabry PBMC cultivation revealed a pro-inflammatory state with increased production of interleukin-1 (IL-1) and TNF- caused by Gb3 accumulation, particularly in dendritic cells and monocytes [45]