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Doses should be titrated up or down by 12.5 25mcg per day, every 6-8 weeks according to effect TSH is the main marker used to monitor the effectiveness of treatment

A substantial body of evidence demonstrates that H.p infection induces significant disruptions to the gut microbiota, characterized by an enrichment of pro-inflammatory bacteria such as Clostridioides difficile, Proteobacteria, Fusobacterium spp., and Prevotella spp., alongside a depletion of beneficial taxa including Lactobacillus spp

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de Paula do Nascimento R, Lima AV, Oyama LM, Paiotti APR, Cardili L, Martinez CAR