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For metabolically stable patients at risk of progression, a very low-protein diet (0.30.4 g/kg/day) supplemented with essential amino acids or ketoacid analogs may be considered under close supervision (276)

Langbein & Leopold, 1970

As an emulsifier, it also prevents ingredients from separating

Injectable depot forms are made by forming microencapsule matrices of the drug in biodegradable polymers such as polylactide-polyglycolide

Both drugs are being developed by Novo Nordisk, likely reflecting a portfolio strategy: CagriSema as the first-to-market injectable combination, and amycretin as a follow-on oral option for patients who prefer pills