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10.1016/j.ejphar.2012.10.032 142 MengH.LiC.FengL.ChengB.WuF.WangX.et al (2007)

167 Hypoxia activates the p38 pathway in rat PAFs, which in turn promotes a proliferative phenotype in fibroblasts and triggers the release of IL-6, which stimulates SMC proliferation via the STAT3 pathway, thereby promoting pulmonary vascular remodeling, with ASK1 potentially involved in this process

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In this review, we introduce several GSH-responsive and -exhausting metal nanomedicines that can specifically ablate tumors based on the high concentration of intracellular GSH in cancer cells