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Relationship between artesunate influence on the process of TGF-beta1 induced alveolar epithelial cells transform into mesenchymal cells and on idiopathic pulmonary fibrosis

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Monocrotaline-induced pulmonary arterial hypertension in rats (wall thickness, total vessel area, heart frequency, QRS axis deviation, QT interval prolongation, increase in right ventricle systolic pressure and bodyweight loss) can be counteracted with early or delayed BPC 157 therapy

Disclosures: Paul Hayashi: Nothing to Disclose, Jasmine Amirzadegan: Nothing to Disclose, Edwige Chiogo Vouffo: Nothing to Disclose, Ling Lan: Nothing to Disclose, Eileen Navarro Almario: Nothing to Disclose, Mark Avigan: Nothing to Disclose 2646 THE PROTECTIVE ROLE OF SULFIREDOXIN-1 (SRXN1) IN ACETAMINOPHEN-INDUCED LIVER INJURY mengyun ke 1 Jongwon Kim 1 Kate S Carroll 2 Wen Xie 1 , 1 University of Pittsburgh, 2 UF Scripps Biomedical Research Background: Acetaminophen (APAP)-induced liver injury is the leading cause of acute liver failure in many Western countries

M., Tofano, R