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These works, despite being in vitro, give great hope for using this molecule as an antibiotic or anti-inflammatory enhancer, through a local administration route such as the inhalation route, to have the greatest concentration of the active in the site of action

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178 In addition, the secreted Cu-binding glycoprotein SPARC (secreted protein acidic and cysteine-rich, also known as osteonectin) has been shown to modulate cellmatrix interactions and promote the invasion and metastasis of tumor cells

doi: 10.1186/s13046-019-1094-2 69 SequeiraE.KaurG.ButtarH