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dihexa depression targets neurotrophic factors like BDNF and NGF, which drive brain repair. By activating the Growth Factors and Their Application in the Therapy of Hereditary Neurodegenerative Diseases Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted GDNF, NGF and BDNF as therapeutic options for neurodegeneration ScienceDirect dihexa mechanism bdnf ngf targets neurotrophic factors like and NGF, which drive brain repair. By activating
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