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Versuchsmusen, deren VDR-Rezeptor abgeschaltet wurde, haben alle Haare verloren

Figure 3 Construction of GSTM1 and GSTT1 knockout mice To further investigate the mechanism by which GSTM1 and GSTT1 are involved in the pathogenesis of acute kidney injury (AKI), we successfully constructed mice with GSTM1 and GSTT1 knockout (GSTM1-KO and GSTT1-KO) using CRISPR-Cas9 technology

Zhu, D., Su, Y., Fu, B

In -thal, elevated EPO stimulates erythroblasts to secrete erythroferrone, which hinders Hepcidin through the BMP-SMAD pathway, leading to iron overload