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Effect of vitamins C and E on progression of transplant-associated arteriosclerosis: a randomised trial

An RCT investigated the effect of 5 mg/d folic acid, the combination of 5 mg/d folic acid and 80 mg/d pyridoxin, and placebo for 3 months

For example, the compound 13 (racemic) is a very week IRAP inhibitor (Lukaszuk et al., 2011) and compound 14 with a 4-hydroxydiphenylmethane scaffold as a substitute for Tyr 2 is essentially inactive (Figure 4) (Andersson et al., 2008)