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Payments: Patients will pay a $50 co-payment monthly, with government covering the remaining costs

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As defined by Arthur Riggs and colleagues, it is "the study of mitotically and/or meiotically heritable changes in gene function that cannot be explained by changes in DNA sequence." [21] The term has also been used, however, to describe processes which have not been demonstrated to be heritable, such as some forms of histone modification

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4,5 Dietary insufficiency, pernicious anemia (i.e., an autoimmune process that reduces available intrinsic factor and subsequent absorption of vitamin B 12 1,2,6,7 ), and long-term use of metformin or acid-suppressing medications have been implicated in B 12 deficiency