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Clinical and preclinical studies have demonstrated significant effects on body weight reduction and metabolic regulation, generating considerable scientific interest in its potential role both as a standalone therapy and in combination with GLP-1 receptor agonists for obesity and metabolic disease research

In conclusion, HIF might promote mitophagy induction in hypoxia by transcriptionally activating the mitophagy factors BNIP3 and BNIP3L

A lot of research on the presence of microplastic in the environment and their consequences on marine species, in terms of physical harm, behavioral changes, tissue lesions, oxidative stress, and gene damage, has been conducted in recent years ( Several studies have documented that aquatic ecosystems across the world have been polluted with microplastic (Zhu et al., 2018

Aquat Toxicol 62:219226 Biswas SK, Rahman I (2009) Environmental toxicity, redox signaling and lung inflammation: the role of glutathione

This discrepancy suggests either the cellular origin of mitochondria, or the activation/metabolic state of the recipient cell influences the reprogramming capabilities