Data Availability The datasets used and/or analysed during the current study are available from the corresponding author on reasonable request
Pathway enrichment analysis further revealed significant activation of pathways related to ribosomal subunit assembly, ribosome biogenesis, mitochondrial respiratory chain function, and purine nucleotide metabolic process in moderate-mutant tumor cells (Fig
see also Section 6.6.6)
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The antioxidant in any of the compositions described in Example 1 and in Tables 17- 19 is substituted with any one of the following antioxidants: antioxidants that do not affect normal mitochondria function, antioxidants that do not affect mitochondrial processing, antioxidants that do enter the mitochondria, but do not affect mitochondrial processing, antioxidants with a molecular weight greater than 500 g/mol, antioxidants with a molecular weight between 200 g/mol and 500 g/mol, antioxidants with a molecular weight of less than 200 g/mol , antioxidants with a standard redox potential between -0.2 V and -0.32 V, antioxidants with a redox potential of -0.06 V, antioxidants with a redox potential of -0.06 V or lower, antioxidants with greater than 5 hydrogen bond donors, antioxidants containing more than 10 hydrogen bond acceptors, and antioxidants with an octanol-water partition coefficient (logP) that exceeds 5