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doi: 10.1371/journal.pone.0214216

Cost Per Dose Comparison (50mg vs 100mg Vials) Monthly Cost by Protocol Larger vials offer better value per milligram but require proper storage and may result in waste if not used within the 30-day reconstituted stability window

There was an apparently shorter median time for the first observable granulation tissue and an apparently faster filling of an open wound with granulation tissue compared to the control group

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What Patients Should Know Right Now The FDAs formal action takes effect April 23, 2026, with the PCAC review of these substances scheduled for July 23-24, 2026