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CRISPR-Cas9 applications include generating precise lipid gene knockouts and enhancing human adipocyte browning capacity, demonstrating significant metabolic improvements in preclinical models (434)

doi: 10.1016/j.pneurobio.2013.12.002 2 AokiJ.KimuraK.MoritaN.HaradaM.MetokiN.TateishiY.et al

Am J Respir Crit Care Med 167 : 395399 Reddy NM, Suryanarayana V, Kalvakolanu DV, Yamamoto M, Kensler TW, Hassoun PM, Kleeberger SR, Reddy SP 2009 Innate immunity against bacterial infection following hyperoxia exposure is impaired in nrf2-deficient mice