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Finally, we expect that the numerous tool compounds, mechanistic insights, cellular target engagement assays, structural information, and biochemical data we make available will be catalytic for the development of GPX4-inhibiting drugs by the academic and pharmaceutical communities

Images were acquired with confocal laser-scanning microscopy (LSM 700, Zeiss) with the same acquisition parameters for the comparison of samples

Protective effect of naringin ameliorates TNBS-induced colitis in rats via improving antioxidant status and pro-inflammatory cytokines

The activation of EMT appears to be related to specific transcriptional programmes induced by DTPs, with certain transcription factors, such as ZEB1, having a substantial role 102

Obvious immune paralysis occurs in the later stage of sepsis, which often indicates poor prognosis and high mortality (274)