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The development of these models were based on observations of increased risk of ASD after exposure to air pollution, pesticides, psychiatric medications and prenatal infections [16]

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Sperm cells rely heavily on antioxidant defenses to protect themselves from oxidative damage, and selenium plays a central role in that process through enzymes such as glutathione peroxidase 4 (GPx4), which helps support normal sperm development and motility.45 Just as importantly, selenium has been studied alongside NAC in human clinical research

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The most plausible explanation is that the non-responders used incorrect administration of the nasal drops