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Of that extracellular fluid, most is in tissues (interstitial, ~7580%) and only about 2025% is in blood vessels

doi: 10.3389/fonc.2022.976224 15 FukushimaTMorimotoMKobayashiSUenoMUojimaHHidakaH

Glutathione (GSH), the brains most prominent intracellular antioxidant, has been suspected to play a key protective role in free-radical-mediated damage to neurons [21], giving rise to the redox dysregulation hypothesis of schizophrenia [22]