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Initiation of Parkinsons disease from gut to brain by delta-secretase

Sun Y et al

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Villin-Cre-ER T2 Ctnnb1 +/lox(ex3) mice were gavaged 5 consecutive days with 1 mg of tamoxifen (Sigma, St Louis, MO, USA) to induce -Catenin activation in enterocytes, as described previously (Gktuna et al, 2014)

further studies are required to clarify these pathways