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J Biol Chem 299:105027

However, as with many experimental compounds, its unregulated nature makes it high-risk for athletes

REDEFINE-1 showed that adding amylin to a GLP-1 backbone improves results

This creates a pharmacokinetic advantage: higher hippocampal exposure with lower systemic exposure reduces the risk of peripheral side effects while maintaining therapeutic receptor activation

If you have questions for me or comments about the podcast or guests or topics that you'd like me to cover on the Huberman Lab podcast, please put those in the comment section on YouTube