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Table 1 Baseline characteristics compared between responders and non-responders

It has been reported that an average of 630% of patients could show vitamin B12 deficiency due to metformin use.[] As per UK MHRA, decreased vitamin B12 levels, or vitamin B12 deficiency, are now considered to be a common side effect in patients on metformin treatment, especially in those receiving a higher dose or longer treatment duration and in those with existing risk factors

Supportive Therapy : Addresses Vitamin B deficiencies and supports energy metabolism

Cobalamin Hypersensitivity Some people might be allergic to cobalamin , the active form of vitamin B12