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Mitochondrial integrity regulated by lipid metabolism is a cell-intrinsic checkpoint for T reg suppressive function

Despite having antimicrobial, antioxidant, and anti-inflammatory activities (Mikelsaar and Zilmer, 2009), it plays a significant role in preventing liver injury

Vigetti D, Clerici M, Deleonibus S, Karousou E, Viola M, Moretto P, et al

Z., Oparil, S., Lucchesi, P., Thompson, J

In this study, we utilized targeted metabolomic profiling to investigate common metabolic alterations in two mechanistically distinct murine models of lung injuryLPS- and papain-induced inflammation