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In leukemia and other cell lines, it causes cell cycle arrest in the G2/M phase, with subsequent cell death unrelated to apoptosis [234]

Internal biliary drainage, unlike external drainage, does not suppress the regeneration of cholestatic rat liver after partial hepatectomy

Low ATP or mitochondrial stress Converting methionine to SAM requires ATP

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In particular, the melatonin peak is associated with the nadir in body temperature, together with maximum tiredness, lowest alertness and performance (59) (Figure 6)