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Secondly, due to the interaction and signal crossing among various components in TME, single-target drugs may not achieve the ideal anti-tumor effect, and the development of multi-target drugs or combination drugs seems to solve this problem

In contrast to apoptosis, necrosis, and autophagy, ferroptosis is characterized by the build-up of lipid reactive oxygen species (ROS) triggering membrane damage

Recently, the hormone fibroblast growth factor 21 (FGF21) has attracted attention as a possible therapeutic agent for the treatment of metabolic disorders, including NAFLD [311]

2013 PMC4019381 Lu, M

Compared with alternative microbial hosts, protein expression in e coli provides unmatched flexibility and scalability