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10.1007/s00277-019-03618-w 15

The 0.1 g of a leaf was pulverized in trichloroacetic acid (TCA) by using a pestle and mortar

Ethacraplatin a dual-threat platinum (IV) prodrug is a cisplatin molecule coordinated to two ethacrynic acid ligands which is able to inhibit irreversibly GSTP1-1 enzymatic activity being reduced and cleaved as a consequence of binding (Fig