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Youre particularly susceptible to B12 depletion if you have dietary inadequacies or medical comorbidities that affect absorption, such as gastrointestinal disorders or pernicious anemia

Oxid Med Cell Longev (2022) 2022:7560569

Anderova et al., 2+ , causing further damage (Unal-Cevik et al., 2004

IFNy not only promotes proteasomal cleavages that determine the C termini of antigenic peptides, but also can (independently of proteasomes) stimulate formation of their N termini by inducing LAP (leucine amino peptidase)

After one week of habitation, female rats were mated overnight during the pro-estrus period and timed pregnant rats (vaginal smear positive, gestational day 0 (G0), gestational term (G22)), which were used for the following experiments