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The complex pathophysiology and the metabolic risk factors shared between type 2 diabetes, obesity, CKD and cardiovascular disease have led to the concept of a cardiovascularkidneymetabolic (CKM) syndrome

These chemicals may impede ferroptosis, an iron-dependent mode of cellular demise, and provide tailored treatment by scavenging reactive oxygen species and averting lipid peroxidation in tumour microenvironments