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As lung elasticity declines, the respiratory system becomes weaker, resulting in a reduction in vital capacity and arterial oxygen pressure (Sharma and Goodwin, 2006)

Concurrently, increased expression of CD57 and NKG2C indicates the expansion of adaptive-like NK cells, which exhibit reduced plasticity and responsiveness

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Activating mutations in SHP2 have been well characterized as oncogenic drivers in hematologic malignancies, including juvenile myelomonocytic leukemia (JMML) and subsets of acute myeloid leukemia (AML), and as germline mutations which underlie Noonan syndrome (NS) 16

An irritated scalp: Hair doesn't grow well on itchy, dry, or irritated scalps