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Amyloid -dependent Mitochondrial Toxicity in Mouse Microglia Requires P2X7 Receptor Expression and Is Prevented by Nimodipine

Gibson, S

Bio-Rad, CA, USA)

The influx of FFAs into the liver leads to an abnormal increase in long-chain fatty acyl-CoA and diacylglycerol (DAG), which in turn activates protein kinase C- (PKC-) (59)