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Tang G, Wang Y, Deng P, Wu J, Lu Z, Zhu R, et al

FGF-2 directly acts on endothelial cells through FGF receptors (FGFRs) to stimulate proliferation and to display a potent angiogenic effect 22,23,24

In one study, researchers used RRBS to investigate genome-wide DNA methylation changes in AD brains, discovering that the CASPASE-4 (CASP4) gene exhibited reduced DNA methylation in AD brains, which was correlated with increased CASP4 expression (54)