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Molecular insights into the pathogenic impact of vitamin D deficiency in neurological disorders

In addition, we examined expressions of BA transporters, Slc10a1 and Slco1a1 (Fig

Given that EtOH-induced mitochondrial dysfunction and ER stress are intimately involved in the pathogenesis of ALD, future studies to examine these pathways under the current experimental setting will provide important mechanistic information underlying the protection seen in GCLM KO mice

In certain embodiments, a ratio of anti CD3 :CD28 antibodies bound to the beads is used such that an increase in T cell expansion is observed as compared to the expansion observed using a ratio of 1 : 1