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doi: 10.1016/j.jhep.2018.09.014

[PubMed: 2720390] 38

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Polysaccharides bind to the Dectin-1/Toll-like receptor (TLR4) receptors on the surface of tumor cells, initiating signal transduction, increasing the expression of pro-apoptotic proteins Bax/Bad, and simultaneously reducing the expression of antiapoptotic proteins Bcl 2

Co-culture of sorted eosinophils with in vitro-generated Th1 or Th2 cells Naive CD4 + CD62L + T cells, purified from the spleens of uninfected C57BL/6N mice using the naive CD4 + T cell isolation kit (Miltenyi Biotec), were stimulated for 3 days with immobilized anti-CD3 (clone 1452C11, BioXCell