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Construct hMLOs using PD causative exogenous stimuli In general, the hMLO models of PD are mainly induced by iPSCs carrying PD-related mutations, with downstream experiments principally study the pathogenic molecular mechanism of mutation-related PD

Youll need to focus on replenishing key nutrients that support neurotransmitter production and cellular repair, particularly B-vitamins, Vitamin D, and essential minerals

But they're not required for typical 28-day use cycles

Kensler and Eaton 2024)

Kong H, Jiang CY, Hu L, Teng P, Zhang Y, Pan XX et al (2019) Morphine induces dysfunction of PINK1/Parkin-mediated mitophagy in spinal cord neurons implying involvement in antinociceptive tolerance