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Moonlighting functions of metabolic enzymes and metabolites in cancer

Increased expression and release of PTGS2 in the prostate is associated with ferroptosis, which promotes arachidonic acid metabolism and the release of inflammatory factors through the upregulation of PTGS2 [11]

Acetylcholinesterase inhibitors for diagnosed cognitive impairment, stimulant medications for ADHD under prescriber supervision, or lifestyle interventions (aerobic exercise, sleep optimization, dietary management) with robust clinical evidence