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Treatment Patients were treated with dosage of B12, mainly intramuscularly ( n = 27, 79.4%), less frequently through the oral route ( n = 4, 11.8%) and even in combination of oral and intramuscular ( n = 2, 5.9%), or combination of intravenous and intramuscular ( n = 1, 2.9%)

Chen, C., Liu, Y., Liu, Y

These differences in molecular features reflect the distinct biological behaviors of tumor cells and their varied responses to treatment, suggesting the clinical necessity of developing personalized treatment strategies based on molecular subtypes

10.1111/j.1365-2265.2009.03644.x 82

5 days/week (~12 mg/day): ~13 vials 3/week (2 mg): ~12 vials 16 weeks: ~3 vials Insulin Syringes (U-100, 1 mL) Per injection: 1 syringe 8 weeks (5 days/week): ~40 syringes 16 weeks (5 days/week): ~80 syringes Bacteriostatic Water (10 mL bottles) Use ~3.0 mL per 50 mg vial for reconstitution