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Such mitochondrial effects allow the evaluation of a wide range of human illnesses (55, 56)

The psychological impact of chronic sleep disruption and discomfort can make treatment more complex, as it may require a holistic approach that addresses both physical and mental health

We summarize these common mechanisms and how disease-specific factors affect them below

The age-related decline in hemoglobin functionality and red cell integrity mirrors broader physiological changes, many of which contribute to frailty, diminished organ performance, and chronic disease progression in the elderly