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Renard et al., 2020

In unstimulated cells, NF-B dimers are usually inactive and held in the cytoplasm by small inhibitory molecules from the NF-B inhibitory proteins family [107]

Table 1 shows the final models parameter estimated values and bootstrap, where the 1,000 bootstraps median values are near to the corresponding final models parameter values, showing that the final model was accurate and reliable

Deubiquitinase USP35, which directly binds with FPN and decreases the ubiquitinated level of FPN, stabilizes FPN to prevent iron overload and ferroptosis in lung cancer cells