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People with underlying medical disorders such as diabetes, cardiovascular disease, lung disease, or cancer are more prone to experience serious illness

doi: 10.1111/j.1360-0443.2005.001127.x

The in vitro PA30 (30% pharmacological activity) derived from tumor cell killing was 0.06 g/mL

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It has also been suggested that propofol appears to exacerbate injury-induced apoptosis through the superinduction of the p75 neurotrophin receptor (p75NTR) and the increased pro-BDNF: mBDNF ratio, leading to a massive disruption of the homeostasis of pro-apoptotic/pro-survival neurotrophic factor signaling [107]