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Most HSCs in the BM are located near the sinus blood vessels, which are in direct contact with HSCs, and their consumption leads to the loss of HSCs [95]

In contrast, cell-based reporter gene assays and in vitro binding assays showed that V730M increases LxxLL binding without affecting FxxLF binding, resulting in increased overall AR transcriptional activity 84

(PubMed) Nishiyama S, Mikeda T, Okada T, Nakamura K, Kotani T, Hishinuma A

Association between gut microbiota and autoimmune thyroid disease: A systematic review and meta-analysis

Trypsin, at 1:50 trypsin-to-protein mass ratio, was added for the first digestion overnight, followed by 1:100 trypsin-to-protein for a second 4 h-digestion