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GSH depletion has been strongly associated with the diseases and loss of function with ageing1

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It is worth noting that the accumulation of reactive oxygen (ROS) in the overactivated central nervous system (CNS) may lead to the gradual destruction of dopaminergic neurons, which is mainly catalyzed by NADPH oxidase (Sharma and Nehru, 2016)

7 In 2020, a group of international experts introduced a novel term MAFLD

Elevated homocysteine has been associated with an increased risk of cardiovascular disease, cognitive decline, pregnancy complications, and other chronic health conditions