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High levels of Drp1 affect T cell activation by enhancing the T cell-induced suppression of lung cancer cells, which increases CD8 + T cell infiltration into the tumor and amplifies the immune system response to treatment with the PD-1 inhibitor pembrolizumab [85]

A.AwadallahS.KhanS

54 A prior study reported that the deletion of TLR9 or Nalp3 markedly weakens APAP-induced hepatic injury, thereby increasing the survival rate of mice