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QiaoXYeLLuJPanCFeiQZhuYet alCurcumin analogues exert potent inhibition on human and rat gonadal 3-hydroxysteroid dehydrogenases as potential therapeutic agents: structure-activity relationship and in silico docking

Because of the structural and functional similarities shared by glutathione and some peptide sequences derived from extracellular loops of aminergic receptors, we decided to compare the binding of ascorbic acid and relevant aminergic and opioid drugs to glutathione and to glutathione-like peptides derived from relevant receptors

The NAD + -consuming enzymes produce NAM as a byproduct, of which high concentrations inhibit the activity of NAD + -consuming enzymes, providing feedback regulation